Publications of Werner Klingler

Original publications:

1. Klingler W#, Heiderich S#, Girard T, Gravino E, Heffron JJ, Johannsen S, Jurkat-Rott K, Rüffert H, Schuster F, Snoeck M, Sorrentino V, Tegazzin V, Lehmann-Horn F. Functional and genetic characterization of clinical malignant hyperthermia crises: a multi-centre study. Orphanet J Rare Dis. 2014; 16;9(1):8. #equal contribution

2. Selig C, Riegger C, Dirks B, Pawlik M, Seyfried T, Klingler W. Bispectral index (BIS) and suppression ratio (SR) as an early predictor of unfavourable neurological outcome after cardiac arrest. Resuscitation. 2014; 85(2):221-226

3. Johannsen S#, Klingler W#, Schneiderbanger D, Heiderich S, Roewer N, Schuster F. Sevoflurane is less sensitive than halothane for in vitro detection of malignant hyperthermia susceptibility. Acta Anaesthesiol Scand 2013;8: 1161-1166 # equal contribution

4. Hoppe K, Lehmann-Horn F, Chaiklieng S, Jurkat-Rott K, Adolph O, Klingler W: In vitro muscle contracture investigations on the malignant hyperthermia like episodes in myotonia congenita. Acta Anaesthesiol Scand 2013; 57: 1017-1023

5. Lehmann-Horn F, Klingler W, Jurkat-Rott K: Correspondence on nonanesthetic malignant hyperthermia. Anesthesiology. 2012; 116:1399-1400

6. Schleip R, Duerselen L, Vleeming A, Naylor IL, Lehmann-Horn F, Zorn A, Jaeger H, Klingler W: Strain hardening of fascia: static stretching of dense fibrous connective tissues can induce a temporary stiffness increase accompanied by enhanced matrix hydration. J Bodyw Mov Ther. 2012 Jan;16(1):94-100.

7. Hafner S, Ehrmann U, Jentzmik F, Klingler W, Georgieff M, Froeba G: Fulminant rhabdomyolysis after prolonged radical prostatectomy managed with continuous veno-venous haemodialysis, regional citrate anticoagulation, and a polysulphone high-flux filter. Br J Anaesth. 2012 ;108(4):702-3.

8. Lehmann-Horn F, Klingler W, Jurkat-Rott K: Nonanesthetic malignant hyperthermia. Anesthesiology. 2011 Nov;115(5):915-7.

9. Klingler W, Lehmann-Horn F, Schulte-Sasse U. Hotline for malignant hyperthermia. New telephone number for the German nationwide 24 h service center: 08221/9600. Anaesthesist. 2011 Feb;60(2):172-4.

10. Holsträter TF, Georgieff M, Föhr KJ, Klingler W, Uhl ME, Walker T, Köster S, Grön G, Adolph O. Intranasal application of xenon reduces opioid requirement and postoperative pain in patients undergoing major abdominal surgery: a randomized controlled trial. Anesthesiology. 2011 Aug;115(2):398-407.

11. Schleip R, Zorn A, Klingler W: Biomechanical properties of fascial tissues and their role as pain generators. Journal of Musculoskeletal Pain. December 2010, Vol. 18 (4): 393-395

12. Zullo A#, Klingler W#, De Sarno C, Ferrara M, Fortunato G, Perrotta G, Gravino E, Di Noto R, Lehmann-Horn F, Melzer W, Salvatore F, Carsana A. Functional characterization of novel ryanodine receptor (RYR1) mutations using a metabolic assay in immortalized B-lymphocytes. Hum Mutat 30: E575-E590 (2009) #contributed equally

13. Schleip R, Klingler W, Lehmann-Horn F. Faszien besitzen eine der glatten Muskulatur vergleichbare Kontraktionsfähigkeit und könnten so die muskuloskeletale Mechanik beeinflussen. Osteopath Med 4:19-21 (2008)

14. Zorn A, F. J. Schmitt, F. H. Hodeck, Schleip R, Weckend F, Klingler W. The spring-like function of the lumbar fascia in human walking. Journal of Bodywork and Movement Therapies. 01/2008; 12:261-263.

15. Schleip R, Vleeming A, Lehmann-Horn F, Klingler W. Letter to the Editor concerning: "A hypothesis of chronic pain: ligament subfailure injuries lead to muscle control dysfunction" (M. Panjabi) Eur Spine J, 16 (10): 1733-1736 (2007)

16. Schleip R, Naylor IL, Ursu D, Melzer W, Zorn A, Wilke HJ, Lehmann-Horn F, Klingler W. Passive muscle stiffness may be influenced by active contractility of intramuscular connective tissue. Med Hypotheses 66(1):66-71 (2006)

17. Schleip R, Klingler W, Lehmann-Horn F: Active fascial contractility: Fascia may be able to contract in a smooth muscle-like manner and thereby influence musculoskeletal dynamics. Med hypotheses 65: 273-277 (2005)

18. Klingler W, Heffron JJ, Jurkat-Rott K, O´Sullivan G, Alt A, Schlesinger F, Bufler J, Lehmann-Horn F. 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) activates skeletal muscle nicotinic acetylcholine receptors. J Pharmacol Exp Ther 314 (3): 1267-1273 (2005)

19. Robinson RL, Anetseder M, Brancadoro V, van Broekhoven C, Carsana A, Censier K, Fort-unato G, Girard T, Heytens L, Hopkins P, Jurkat-Rott K, Klingler W, Kozak-Ribbens G, Krivosic-Horber R, Monnier N, Nivoche Y, Olthoff D, Rueffert H, Sorrentino V, Tegazzin V, Mueller C. Recent advances in the diagnosis of malignant hyperthermia susceptibility: How confident can we be of genetic testing? Eur J Hum Genetics 11: 342-8 (2003)

20. Wappler F, Anetseder M, Baur CP, Censier K, Doetsch S, Felleiter P, Fiege M, Fricker R, Halsall PJ, Hartung E, Heffron JJ, Heytens L, Hopkins PM, Klingler W, Lehmann-Horn F, Nivoche Y, Tegazzin V, Tzanova I, Urwyler A, Weisshorn R, Schulte am Esch J: Multicentre evaluation of in vitro contracture testing with bolus administration of 4-chloro-m-cresol for diagnosis of malignant hyperthermia susceptibility. Eur J Anaesthesiol 20(7):528-36 (2003)

21. Klingler W, Baur C, Georgieff M, Lehmann-Horn F, Melzer W: Detection of proton release from cultured human myotubes to identify malignant hyperthermia susceptibility. Anesthesiology 97:1059-1066 (2002)
(Begleitendes Editorial: Allen PD, Lopez JR: "Noninvasive" Testing for Malignant Hyperthermia Susceptibility. Anesthesiology 97:1045-1046, 2002)

22. Klingler W, Kreja L, Nothdurft W, Selig C: Influence of different radioprotective compounds on radiotolerance and cell cycle distribution of human progenitor cells of granulocytopoiesis in vitro. Br J Haematol 119:244-254 (2002)

23. Baur C, Bellon L, Felleiter P, Fiege M, Fricker R, Glahn K, Heffron JJ, Herrmann-Frank A, Jurkat-Rott K, Klingler W, Lehane M, Ording H, Tegazzin V, Wappler F, Georgieff M, Lehmann-Horn F. A multicenter study of 4-chloro-m-cresol for diagnosing malignant hyperthermia susceptibility. Anesth Analg 90(1):200-5 (2000)

24. Baur C, Klingler W, Jurkat-Rott K, Froeba G, Schoch E, Marx T, Georgieff M, Lehmann-Horn F. Xenon does not induce contracture in human malignant hyperthermia muscle. Br J Anaesth 85:712-716 (2000)

25. Lerche H, Biervert C, Alekov AK, L. Schleithoff L, Lindner M, Klingler W, Bretschneider F, Mitrovic N, Jurkat-Rott K, Bode H, Lehmann-Horn F, Steinlein OK. A reduced K+ current due to a novel mutation in KCNQ2 causes neonatal convulsions. Ann Neurol 46: 305-312 (1999)

26. Brandt A, Schleithoff A, Jurkat-Rott K, Klingler W, Baur C, Lehmann-Horn F. Screening of the ryanodine receptor gene in 105 malignant hyperthermia families: novel mutations and concordance with the in-vitro contracture test. Hum Mol Gen 8 (11):2055-2062 (1999)

Reviews:

1. Hoppner A, Klingler W. Erkennen und Behandeln des Status epilepticus. Notfall + Rettungsmedizin. 2014; 17(1): 69-80

2. Klingler W, Jäger H, Pedro M, Schleip R. Faszien als Ursache von Schmerzsyndromen. Aktuelle Schmerzmedizin. 2014 (4): 1-7

3. Klingler W, Weiß G, Bäzner U, Lehmann-Horn F: Maligne Hyperthermie – Was gibt es Neues? Journal für Anästhesie und Intensivbehandlung 2013;1: 80-84

4. Schleip R, Jäger H, Klingler W: What is 'fascia'? A review of different nomenclatures. J Bodyw Mov Ther. 2012;16(4): 496-502.

5. Klingler W, Jurkat-Rott K, Lehmann-Horn F, Schleip R: The role of fibrosis in Duchenne muscular dystrophy. Acta myologica 2012; 31: 184-195

6. Klingler W, Rueffert H, Lehmann-Horn F, Girard T, Hopkins PM. Core myopathies and risk of malignant hyperthermia. Anesth Analg 109: 1167-1173 (2009)

7. Klingler W, Dirks B. Gehirne in Not richtig behandeln. CME - Premiumfortbildung 5(9): 7–15 (2008)

8. Klingler W, Dirks B. Neurologische Notfälle nach Leitsymptomen. Notfall Rettungsmed, 10 (2): 147-160 (2007)

9. Klingler W, Dirks B. Untersuchung des Bewusstlosen. Notfall Rettungsmed, 10 (3): 239-246 (2007)

10. Klingler W, Lehmann-Horn F, Jurkat-Rott K: Complications of anaesthesia in neuromuscular disorders. Neuromuscul disord 15(3): 195-206 (2005)
Dieser Artikel gehörte vom Erscheinen bis Anfang 2008 zu den TOP25-Downloads von Neuromuscular Disorders http://top25.sciencedirect.com/?journal_id=09608966

case reports:

1. Hoppe K, Dirks B, Stahl W, Muth CM, Klingler W: ECG misinterpretion underneath high-voltage power lines. Resuscitation 80: 973–974 (2009)

2. Pawlik, MT, Seyfried T, Riegger C, Klingler W, Selig C: Bispectral index monitoring during cardiopulmonary resuscitation repeated twice within 8 days in the same patient: a case report. Int J Emerg Med 1(3): 209-212 (2008)

3. Hege-Scheuing G, Klingler W: Therapiebegrenzung, Therapiebeendigung und die Frage nach einem würdigen Tod. Notfall Rettungsmed 11(7): 487-490 (2008)

Book chapters:

1. Schleip R, Jäger H, Klingler W: Chapter 4.2 How cells modulate the tonicity and architecture of fascial tissues. In Schleip R, (Hrsg.) Fascia. The tensional network of the human body. 2012 ISBN 978-0-7020-3425-1, p 157-164

2. Thomas J, Klingler W: Chapter 4.4 The influence of pH and other metabolic factors on fascial properties. In Schleip R, (Hrsg.) Fascia. The tensional network of the human body. 2012 ISBN 978-0-7020-3425-1, p 171-176

3. Klingler W: Chapter 7.18 Temperature effects on fascia. In Schleip R, (Hrsg.) Fascia. The tensional network of the human body. 2012 ISBN 978-0-7020-3425-1, p 421-424

4. Schleip R, Jäger H, Klingler W: Chapter 4.2 How cells modulate the tonicity and architecture of fascial tissues. In Schleip R, (Hrsg.) Fascia. The tensional network of the human body. 2012 ISBN 978-0-7020-3425-1, p 157-164

5. Schleip R, Zorn A, Lehmann-Horn F, Klingler W: The fascial network: an exploration of its load bearing capacity and its potential role as a pain generator. in Vleeming et al. Proceedings of the 7th Interdisciplinary World Congress on Low Back & Pelvic Pain, Los Angeles, November 9-12, 2010, ISBN 978-90-816016-1-0, p 215-218

6. Klingler W, Maier B, Dirks B. Kapitel 3: Erweiterte Diagnostik. In Dirks B (Hrsg): Die Notfallmedizin, Springer Verlag, Heidelberg 2007 ISBN: 978-3-540-25608-3

7. Schleip R, Klingler W, Lehmann-Horn F: Fascia is able to contract in a smooth muscle-like manner and thereby influence musculosceletal mechanics. In Liepsch D (Hrsg): 5th World congress of Biomechanics Medimond Verlag, Bologna, Italien 2006 ISBN: 88-7587-270-8

8. Myofibroblast Density in Fasciae. R. Schleip, S. Rankl, A. Zorn, F. Lehmann-Horn, W. Klingler. 01/2009; In book: Fascia Research II, Publisher: Urban, Editors: P. A. Huijing, A. P. Hollander, T. W. Findley, R. Schleip, pp.219

9. Contractile Properties of Rat Fascia. R. Schleip, A. Klein, S. Rankl, A. Zorn, M. Martin, F. Lehmann-Horn, W. Klingler. 01/2009; In book: Fascia Research II, Publisher: Urban, Editors: P. A. Huijing, A. P. Hollander, T. W. Findley, R. Schleip, pp.92

10. I. L. Naylor, A. Zorn, R. Schleip, W. Klingler. The contractility of rat myofibroblasts - a review of the evidence for 'receptors', putative agonists and potential anti-contractile drugs. 01/2007; Chapter in book. Fascia Research. ISBN: 978-3-437-55009-6 Publisher: Urban & Fischer, Editors: T. W. Findley, Schleip, pp.81

Posters and conference proceedings (selection):

1. Eingeladener Vortrag
Klingler W: Was tut weh, Muskel oder Faszie? Süddeutsches Symposium des Verbandes physikalische Therapie VPT, 25.1.2014, Stuttgart

2. Eingeladener Vortrag
Klingler W: Das Fasziennetzwerk: vom biomechanischen Servomechanismus zum Schmerzgenerator, Deutscher Kongress für Orthopädie und Unfallchirurgie DKOU 2013, 25.10.2013, Berlin

3. Posterbeitrag, ausgewählt für Kurzvortrag
Dennenmoser S, Schleip R, Klingler W: Exercise and therapeutic interventions. Electrical impedance combined with sono-elastography as a tool for the examination of lumbar fascia. 8th interdisciplinary world congress on low back & pelvic pain. 27.-31.10.2013, Dubai, VAE

4. Eingeladener Vortrag
Klingler W: Bindegewebe als Ursache für Schmerzsyndrome im Sport. Deutscher Sportärztekongress. Goethe-Universität, 6.9.2013, Frankfurt

5. Eingeladener Vortrag
Klingler W: Die Rolle der Faszien bei der Akupunktur. DÄGFA Symposium, Anästhesiologie, Ludwig-Maximilian-Universität, 19.10.2013, München

6. Eingeladener Vortrag
Klingler W: Was ist wahr? – Das Wissen über das myofasziale System in der Übersicht. Rheumasymposium 2013, 29.6.2013, Bad Füssing

7. Eingeladener Vortrag
Klingler W: Fascia - from cell biology to clinical application. ECOSEP Conference, 25.-27.4.2013, Frankfurt

8. Eingeladener Vortrag
Klingler W: Myofasziale Schmerzen - Was gibt es Neues? Deutscher Anästhesie Kongress DAC 2013, 20.-22.4.2013, Nürnberg

9. Koorganisation, Vortrag und Vorsitz
Klingler W: Overview - Connective tissue in sports medicine. Connective tissue in Sports medicine. 12.-14.4.2013, Ulm

10. Eingeladener Vortrag
Klingler W: Maligne Hyperthermie – Was gibt es neues? Symposium Intensivmedizin und Intensivplege, 13.-15.2.2013 Bremen

11. Eingeladener Vortrag
Klingler W: Welche Bedeutung haben Faszien bei der Schmerzentstehung? 01.03.2013; 17. Internationales Wiener Schmerzsymposium, Wien, Österreich

12. Eingeladener Vortrag
Klingler W: Rhabomyolyse als anästhesiologische Komplikation. Anästhesiologische Fortbildungsreihe 10.12.2012 Klinikum Memmingen

13. Eingeladener Vortrag
Klingler W: Biologische und physikalische Eigenschaften von Faszien. Jahreshauptversammlung. Verband physikalische Therapie Bayern. 24.11.2012, Ismaning

14. Eingeladener Vortrag und Vorsitz
Klingler W: Physiologische Eigenschaften von Faszien. XV. Interdisziplinäres Symposium, Medizin – Physiotherapie – Sportwissenschaft. 23.11.2012, Regensburg

15. Eingeladener Vortrag
Klingler W: Fasziale Schmerzen. Treffen der Neuromuskulären Zentren Baden-Württembergs am 7.11.2012 in Ulm

16. Eingeladener Vortrag
Klingler W. Faszienphysiologie und -pathophysiolgie. Jahrestagung der Bayerischen Sportärzte. Germering 19.-20.10.2012

17. Eingeladener Vortrag:
Klingler W: Zur Kontraktilität von Faszien. XXIII Jahrestagung. Sportphysiotherapie. Deutscher Olympischer Sportbund. Frankfurt 29.09.2012

18. Koorganisation und Vorsitz:
Klingler W: Arbeitsgemeinschaft Deutschsprachiger Neuroanästhesisten und Neurointensivmediziner. Günzburg, ADNANI 23.6.2012

19. Posterbeitrag:
Barty G, Schleip R, Jäger H, Klingler W: Fascia as a Sensory Organ: A Literature Review of the Sensory Innervation of Muscular Fascia. Vancouver Fascia Research Conference 2012

20. Posterbeitrag:
Dennenmoser S, Schleip R, Klingler W: Sono-Elastography Combined with Electrical Impedance as a Tool for the Examination of Lumbar Fascia. Vancouver Fascia Research Conference 2012

21. Posterbeitrag:
Jäger H, Klingler W, Lehmann-Horn F, Schleip R. Do calcium activated potassium channels control proliferation of myofibroblasts? Implications for fibroproliferative diseases. Vancouver Fascia Research Conference 2012

22. Posterbeitrag:
Gordon C, Ereline J, Jäger H, Klingler W, Schleip R: Assessment of Myofascial Trigger Point Release with a novel Myometer (MyotonPRO) in addition to an Algometer; Vancouver Fascia Research Conference 2012

23. Eingeladener Vortrag:
Klingler W.: Myofascial Pain Syndromes. The 3rd Bienniel Exercise Induced Leg Pain Symposium. London, 25. und 26. Jan 2012

24. Eingeladener Vortrag:
Klingler W: Update Maligne Hyperthermie. Kreiskrankenhaus Krumbach, 17.10.2011

25. Posterbeitrag:
Johannsen S, Klingler W, Metterlein T, Roewer N, Schuster F:
Ist die Bolusgabe von Sevofluran im In-vitro Kontrakturtest zur MH-Diagnostik geeignet? Deutscher Anästhesiekongress Hamburg, Mai 2011

26. Koorganisation und Vortrag
Klingler W: Maligne Hyperthermie. Jahrestagung Wissenschaftlicher Arbeitskreis Neuroanästhesie (WAKNA), Universität Ulm, Reisensburg 12.11.2011

27. Vortrag:
Klingler W: Maligne Hyperthermie. Was gibt es Neues? Kreiskrankenhaus Biberach, Biberach 12.04.2011

28. Posterbeitrag
Klingler W, Schleip R: "Heat induced fascial relaxation". 7th Interdisciplinary World Congress on low back pain. Los Angeles, USA 8.-12. Nov 2010

29. Vortrag:
Klingler W: Maligne Hyperthermie: Facts and Fiction. Universitätsklinik für Anästhesiologie, Universität Ulm, 03.05.2010

30. Vortrag:
Klingler W: Update Maligne Hyperthermie, Universitätsklinik für Anästhesiologie, Universität Ulm, 17.06.2009

31. Vortrag:
Klingler W, Riegger C, Seyfried T, Dinse-Lambracht A, Schmidt C, Pawlik M, Selig C: Monitoring des bispektralen Index (BIS) bei der kardiopulmonalen Reanimation. Treffen der wissenschaftlichen Arbeitsgruppe der DGAI Bereich Notfallmedizin, Kiel, Februar 2009. Notfall Rettungsmed Suppl 1, 2009: 3

32. Poster:
Schleip R, Klein A, Rankl S, Zorn A, Martin M, Lehmann-Horn F, Klingler W. Contractile properties of rat fascia. 2nd International Fascia Research Congress, Amsterdam, Oktober 2009

33. Poster:
Schleip R, Rankl S, Zorn A, Lehmann-Horn F, Klingler W. Myofibroblast density in fasciae. 2nd International Fascia Research Congress, Amsterdam, Oktober 2009

34. Eingeladener Vortrag:
Klingler W. Faszien - mehr als nur passive Kraftüberträger. Kongress des Zentralverbands der Ärzte für Naturheilverfahren und Regulationsmedizin, Freudenstadt, März 2009

35. Poster:
Seyfried T, Klingler W, Riegger C, Selig C, Graf B, Pawlik M. BIS-Monitoring zeigt signifikante Unterschiede in der Neurologie von Überlebenden nach Reanimation. Jahrestagung der Deutschen Gesellschaft für Anästhesiologie und Intensivmedizin, Deutscher Anästhesiekongress, Leipzig, Mai 2009

36. Vortrag:
Klingler W: Influence of temperature on connective tissue - implications for the treatment of low back pain. GEOS Meeting, Mulhouse, Frankreich, März 2009

37. Eingeladener Vortrag:
Klingler W: Organizational and operational structure of a German University hospital operating theatre. Department of Occupational Health, Mahidol University, Bangkok, Thailand, April 2009

38. Eingeladener Vortrag:
Klingler W. Reanimation mit Autopulse und BIS, Symposium Anästhesie, Krumbach, Nov 2008

39. Poster und publiziertes Abstract:
Schleip R, Klingler W. Chronic low back pain may originate from subfailure in lumbar fasciae. J Bodywork Mov Ther. 12 (3): 263 (2008)

40. Poster und publiziertes Abstract:
Schleip R, Klingler W. Fascial strain hardening correlates with matrix hydration changes. J Bodywork Mov Ther. 12 (4): 387 (2008)

41. Poster:
Zorn A, Schmitt FJ, Hodeck KF, Schleip R, Klingler W. The elastic function of the lumbar fascia in human gait. European Workshop on Movement Science, Amsterdam, Niederlande, Juni 2007

42. Poster und publiziertes Abstract:
Schleip R, Zorn A, Lehmann-Horn F, Klingler W. Fascia is able to actively contract and thus may influence musculoskeletal dynamics. Forsch Komplementärmed 14(suppl1):14, 2007

43. Vortrag:
Klingler W, Lehmann-Horn F, Schleip R. Influence of connective tissue on in vitro contracture testing for malignant hyperthermia (MH). Annual Meeting of the European Malignant Hyperthermia Group, Siena, Italien, Mai 2007

44. Poster:
Zullo A#, Klingler W#, De Sarno C, Ferrara M, Fortunato G, Perrotta G, Gravino E, Di Noto R, Lehmann-Horn F, Melzer W, Salvatore F and Carsana A. Mutations in the RYR1 gene and their functional characterization in immortalized lymphocytes by detection of proton release rate. Annual Meeting of the European Malignant Hyperthermia Group, Siena, Italien, Mai 2007 #contributed equally

45. Poster und publiziertes Abstract:
Schleip R, Zorn A, Lehmann-Horn F, Klingler W. Fascia may influence musculoskeletal dynamics. Forsch Komplementarmed 14 (suppl 1), 15, 2007

46. Poster:
Klingler W, Schlegel C, Schleip R. The role of fascia in resting muscle tone and heat induced relaxation. Fascia Research Conference, Harvard, USA, Oktober 2007

47. Poster:
Schleip R, Klingler W. Chronic low back pain may originate from subfailure injuries of lumbar fasciae. Fascia Research Conference, Harvard, USA Oktober, 2007

48. Eingeladener Vortrag:
Klingler W, Schleip R. Eingeladener Vortrag. Idendification of myofibroblasts in fasciae. Fascia Research Conference, Harvard, USA, Oktober, 2007

49. Poster:
Schleip R, Klingler W. Fascial Strain Hardening is Correlated to Matrix Hydration Changes. Fascia Research Conference, Harvard, USA Oktober, 2007

50. Poster (mit Auszeichnung):
Klingler W, Schleip R. Contractile features of human fascia. 6th interdisciplinary World Congress on Low Back & Pelvic Pain. Barcelona, Spanien, November, 2007

51. Vortrag:
Zorn A, Schmitt FJ, Hodeck KF, Schleip R, Klingler W. The spring-like function of the lumbar fascia in human walking. Fascia Research Conference, Harvard, USA Oktober 2007

52. Poster:
Schleip R, Klingler W, Lehmann-Horn F. Human lumbar fascia is able to actively contract and thereby influence low back stability. 6th International Scientific Conference on Prevention of Work-Related Musculoskeletal Disorders, Boston, USA, August 2007

53. Vortrag:
Klingler W, Lehmann-Horn F, Schleip R. Influence of connective tissue on in vitro contracture testing for malignant hyperthermia (MH). Annual Meeting of the European Malignant Hyperthermia Group. Siena, Italien, Mai, 2007

54. Eingeladener Vortrag:
Klingler W: Motor endplate as a physiological target of the illicit drug ecstasy. Young investivator award, DPG- and FEPS conference, März 2006

55. Poster und publiziertes Abstract:
Sartorius T, Wietzorek G, Chaiklieng S, Klingler W, Ursu D, Knaus H, Melzer W, Jurkat-Rott K, Ruth P, Lehmann-Horn F. BK channel deficiency prevents low Cl- conductance myotonia, probably via reduced T-tubular K+ accumulation. Acta physiologica 186 (Suppl. 1): 190, 2006

56. Poster und publiziertes Abstract:
Schleip R, Klingler W, Lehmann-Horn F. Fascia is able to contract in a smooth muscle-like manner and thereby influence musculoskeletal mechanics. J Biomechanics 39 (Suppl1): S488, 2006

57. Poster und publiziertes Abstract:
Chaiklieng S, Klingler W, Lehmann-Horn F. Effects of osmolarity and [K+]o on the warm-up phenomenon in myotonic muscle. Acta physiologica 186 (Suppl. 1): 223, 2006

58. Poster und publiziertes Abstract:
Schlegel C, Klingler W, Chaiklieng S, Lehmann-Horn F. Influence of temperature on low Cl- conductance myotonia in vitro. Acta physiologica 186 (Suppl. 1): 225, 2006

59. Poster und publiziertes Abstract:
Klingler W, Heffron JJA, Jurkat-Rott K, O´Sullivan G, Alt A, Schlesinger F, Bufler J, Lehmann-Horn F: Motor endplate as a physiological target of the illicit drug ecstasy. Acta physiologica 186 (Suppl. 1): 226, 2006

60. Poster und publiziertes Abstract:
Schleip R, Klingler W, Lehmann-Horn F: Fascia is able to contract and relax in a smooth muscle like manner. Acta physiologica 186 (Suppl. 1): 247, 2006

61. Vortrag:
Klingler W: Update MH. Mittwochsfortbildung Uniklinik für Anästhesie, Universität Ulm, März 2006

62. Poster:
Schleip R, Klingler W: Active facial contractility: Fascia is able to contract and relax in a smooth muscle-like manner and thereby influence biomechanical behavior. Connecting Tissue and Medicine - a conference for scientists and manual therapy practitioners. East Orange Veterans Association Medical Center, East Orange, New Jersey, USA, August 2005

63. Poster:
Chaiklieng S, Lehmann-Horn F, Klingler W: Antimyotonic effects of elevated K+-concentration and osmolarity. XXXIV European Muscle Conference, Hortobagy, Ungarn, September 2005

64. Poster:
Klingler W, Heffron JJA, Jurkat-Rott K, O´Sullivan G, Alt A, Schlesinger F, Bufler J, Lehmann-Horn F: Nicotinic acetylcholine receptors as a physiological target of the illicit drug ecstasy. XXXIV European Muscle Conference, Hortobagy, Ungarn, September 2005

65. Poster:
Zullo A, Desarno C, Klingler W, Carsana A, Fortunato G, Lehmann-Horn F, Melzer W, Salvatore F: Metabolic overreaction in response to 4-chloro-m-cresol in immortalized B-lymphocytes from malignant hyperthermia susceptible individuals with a novel RyR1 mutation. XXXIV European Muscle Conference, Hortobagy, Ungarn, September 2005

66. Poster:
Schleip R, Klingler W: Fascia may be able to contract and relax in a smooth muscle-like manner and thereby influence musculoskeletal dynamics. International Congress of Osteopathic Medicine, Freiburg, September 2005

67. Poster:
Schleip R, Klingler W: Active fascial contractility: Fascia is able to contract and relax in a smooth muscle-like manner and thereby influence biomechanical behavior. IASI Symposium, Seattle, Washington, USA, Oktober 2005

68. Poster:
Zullo A, De Sarno C, Klingler W, Fortunato G, Gravino E, Coccia M, Savoia D, Lehmann-Horn F, Melzer W, Salvatore F, Carsana A: Functional characterization of novel RYR1 mutations using a metabolic assay of B-lymphocytes. 12th European Conference of Clinical Molecular Biology, Neapel, Italien, November 2005

69. Vortrag:
Klingler W: Neurologische Notfälle. Deutsches Rotes Kreuz Ulm, April 2005

70. Vorträge:
Klingler W: Praktische Übungen, Neurologische Notfalldiagnostik, Deutsches Rotes Kreuz Ulm Mai/Juni 2005

71. Vortrag:
Klingler W: Neurologische Notfälle. Fortbildungsveranstaltung, Abteilung für Anästhesiologie, Universität Ulm, Juni 2005

72. Poster:
Chaiklieng S, Klingler W, Lehmann-Horn F: Antimyotonic effects of elevated K+ concentration. Graduate College 460 Ulm University, Juni 2004

73. Poster:
Schleip R, Klingler W, Lehmann-Horn F: Active contraction of the thoracolumbar fascia – indications of a new factor in low back pain research with implications for manual therapy. 5th Interdisciplinary World Congress on Low Back & Pelvic Pain, Melbourne, Australien November 2004

74. Vortrag:
Klingler W, Heffron J, O'Sullivan G, Alt A, Georgieff M, Lehmann–Horn F. Ecstasy exerts succinylcholine-like effects on skeletal muscle. International Workshop on Malignant Hyperthermia, Brunnen, Schweiz, Juni 2003

75. Vorsitz:
Klingler W, Teggazin V, Islander G. Alternative testing. International Workshop on Malignant Hyperthermia, Antwerpen, Belgien, 2002

76. Vortrag:
Hack G, Jurkat-Rott K, Baur C, Melzer W, Lehmann-Horn F, Klingler W: The acidification rate of human B lymphocytes after stimulation with 4-CmC is significantly higher in MHS compared to MHN-individuals. International Workshop on Malignant Hyperthermia, Paris, Frankreich, Mai 2001

77. Poster:
Hack G, Jurkat-Rott K, Baur C, Melzer W, Lehmann-Horn F, Klingler W: Measurements of the acidification rate of human B lymphocytes for the identification of the Malignant Hyperthermia Susceptibility. Tagung der Deutschen Physiologischen Gesellschaft, Berlin, März 2001

78. Vortrag:
Klingler W, Hack G, Jurkat-Rott K, Baur C, Melzer W, Lehmann-Horn F. Measurements of the metabolic activity of human myotubes for the identification of the malignant hyperthermia susceptibility. International Workshop on Malignant Hyperthermia, Hamburg, 2000

79. Poster und publiziertes Abstract:
Klingler W, Baur C, Hafner F, Grocki K, Georgieff M, Lehmann-Horn F, Melzer W. Measurements of the proton secretion rate of human myotubes for the identification of the malignant hyperthermia susceptibility. Pflügers Arch - Eur J Physiol 437 (5):R41-R196, 1999

80. Poster:
Brandt A, Schleithoff L, Jurkat-Rott K, Klingler W, Baur C, Lehmann-Horn F. Screening of the ryanodine receptor gene in 105 malignant hyperthermia families: novel mutations and concordance with the in-vitro contracture test
International Workshop of Malignant Hyperthermia, Kopenhagen, Schweden, August 1999

81. Poster:
Baur C, Bellon L, Felleiter P, Fiege M, Fricker, R, Glahn K, Heffron JJA, Klingler W, Lehane M, Ording H, Tegazzin V, Wappler F, Georgieff M and Lehmann-Horn F. Chlorocresol for malignant hyperthermia testing: results of the European multicenter study. International Workshop of Malignant Hyperthermia, Kopenhagen, Schweden, August 1999

82. Vortrag:
Klingler W, Baur C, Hafner F, Grocki K, Georgieff M, Lehmann-Horn F, Melzer W. Measurements of the cellular acidification of human myotubes: a possible tool for the identification of malignant hyperthermia susceptibility? International Workshop of Malignant Hyperthermia, Kopenhagen, Schweden, August 1999

83. Poster:
Wappler F, Anetseder M, Baur C, Doetsch S, Felleiter P, Fiege M, Fricker R, E Hartung, Heffron JJA, Heytens L, Hopkins PM, Klingler W, Nivoche Y, JF Payen V Tegazzin V, Tzanova I, Urwyler A, von Arx E. In-vitro contracture testing with bolus administration of 4-chloro-m-cresol for diagnosis of malignant hyperthermia susceptibility: a European multicenter study. International Workshop of Malignant Hyperthermia, Kopenhagen, Schweden, August 1999

84. Poster:
Klingler W, Maier S, Thomasky N, Wrisch A, Bretschneider F, Malina T, Schleithoff L. Kopplungsanalysen bei proximaler myotoner Myopathie und benignen familiären infantilen Krämpfen. IZKF Uni Ulm, Juni 1999

85. Poster:
Baur C, Schreiber H, Klingler W, Ludolph A, Georgieff M, Lehmann-Horn F. Screening for neuromuscular diseases in patients suspicious of malignant hyperthermia. Meeting of the European Malignant Hyperthermia Group, Neapel, Italien, Mai 1998

86. Poster:
Baur C, Marx T, Klingler W, Georgieff M, Lehmann-Horn F. Xenon and Malignant Hyperthermia Susceptibility: In vitro Results. Deutscher Anästhesiekongreß, Frankfurt, Juli 1998

87. Poster:
Brandt A, Schleithoff L, Klingler W, Baur C, Lehmann-Horn F. Evaluation of the 17 known RyR1 mutations in 100 MHS-families. Meeting of the European Malignant Hyperthermia Group, Neapel, Italien, Mai 1998